Department of Laboratory Medicine

Department of Laboratory Medicine of FN Nitra provides a wide range of routine and specialized tests in clinical biochemistry, hematology, blood bank, clinical immunology and allergology, the medical genetics laboratory, and the pharmacology laboratory.

Daytime operating hours: 7:00–15:00
Biochemistry, hematology and blood bank – 24-hour operation

 

Department of Clinical Biochemistry

Department of Clinical Biochemistry is part of the Department of Laboratory Medicine of FN Nitra. The main activity of the OKB is performing laboratory examinations of biological materials using physical, physicochemical, chemical, and immunochemical methods within the scope of the approved range for all inpatient and outpatient departments and for external applicants or self-payers. Payment for these examinations is according to the valid price lists issued by FN Nitra.

We determine a very wide spectrum of basic and specific biochemical parameters related to the examination of disorders of carbohydrate, protein, non-protein nitrogen metabolism, hemoglobin and its derivatives, lipoprotein metabolism, enzymes, as well as hormones, tumor markers, thyroid, cardiac, hepatic or bone markers, parameters monitoring anemia; we offer serum protein ELFO examination, immunofixation, etc.

The quality of work is regularly monitored in the external quality assessment cycles of SEKK s.r.o. Pardubice – Czech Republic and in the external quality assessment cycles of RIQAS by RANDOX United Kingdom.

Alphabetical list of OKB examinations

OKB Request form

Department of Hematology

The laboratory section – hematology and hemocoagulation laboratory – provides basic and special hematological and hemocoagulation examinations.

The quality of work of the laboratory section is regularly monitored in the external quality assessment cycles of SEKK spol s.r.o. Pardubice.

HTO-Examinations

HTO Request form

Blood Bank

The Blood Bank is part of the OLM

The Blood Bank performs blood group and Rh factor testing, screening for anti-erythrocyte antibodies, Coombs tests, compatibility testing, determination of certain group and Rh erythrocyte antigens, and pre-transfusion examinations. It organizes the purchase, storage, and dispatch of transfusion products to individual departments of the FN.

The quality of work is regularly monitored in the external quality assessment cycles of SEKK spol s.r.o. Pardubice.

Indication criteria for hemotherapy at FN Nitra

Methodological guidelines – administration of transfusion medicinal products at Nitra University Hospital

Methodological guidelines on the prevention and reporting of transfusion reactions at Nitra University Hospital

Organizational arrangements for preoperative blood collection for autologous transfusions

Department of Clinical Immunology and Allergology

Department of Clinical Immunology and Allergology

It is a clinical and laboratory field dealing with the study, diagnosis, and treatment of patients with diseases or pathological processes resulting from disorders of immunological mechanisms, as well as diseases where influencing immunity is an important part of treatment or prevention.

The laboratory section of clinical immunology and allergology is an integral part of the Department of Laboratory Medicine of FN Nitra. It also cooperates closely with the outpatient component of OKIA, MUDr. Vrbicová.

The quality of work is regularly monitored in the external quality assessment cycles of SEKK spol. s r.o. Pardubice, Czech Republic and RfB Referenzinstitut Bonn, Germany.

List of examinations

OKIA Request form

Medical Genetics Laboratory

The Medical Genetics Laboratory is part of the Department of Laboratory Medicine of the Nitra University Hospital. The facility is closely linked with the Medical Genetics Clinic, where MUDr. Silvia Vogelová operates.
We provide cytogenetic and molecular genetic examinations in the field of prenatal and postnatal diagnostics, hereditary diseases, pharmacogenetics, and molecular genetic examinations from paraffin blocks (FFPE). The quality of work is regularly monitored in the external quality assessment cycles of SEKK, spol. s r. o., Pardubice, Czech Republic.

Diagnosticians:
RNDr. Andrea Kollárová
  • andrea.kollarova@fnnitra.sk
  • 037/6545 735
RNDr. Alexandra Pôbišová, PhD., MPH
  • alexandra.pobisova@fnnitra.sk
  • 037/6545 735
Laboratory technicians:
Mgr. Mária Mentová
  • 037/6545 243

Request form for molecular genetic examinations from blood

Request form for molecular genetic examinations from FFPE

Request form for cytogenetic examinations

 

 

Clinical Pharmacology

Clinical Pharmacology,within the Internal Clinic and the Department of Laboratory Medicine

The Department of Clinical Pharmacology was established in January 1990. Currently, clinical pharmacologists (MUDr. Karin Máčalová, MUDr. Marek Rác) work within the Internal Clinic and a clinical pharmacist (PharmDr. Mária Göböová, PhD.) works within the Internal Clinic and the pharmacokinetic laboratory (Department of Laboratory Medicine).

Currently, we provide expert consultations in the field of antibiotic treatment, drug risks (interactions, adverse effects, and drug intolerance), optimization of dosage regimens for individual patients, pharmacotherapy in pregnancy and lactation, and drug risks in elderly and specific patient groups. Expert consultations include both hospitalized and outpatient patients.

Since 1992, we have been providing a complete pharmacokinetic service, which includes therapeutic drug monitoring (TDM) using the immunoassay method and toxicological drug screening.

Currently, we monitor levels of: amikacin, benzodiazepines, cyclosporine, digoxin, phenobarbital, gentamicin, carbamazepine, valproic acid, opiates, theophylline, vancomycin. Toxicological examination of drugs and medications is determined in urine. We currently measure concentrations of addictive drugs and medications: amphetamine, benzodiazepines, buprenorphine, cannabinoids, opiates. We interpret every TDM result and propose optimal dosage regimens for the individual patient, evaluating interactions of the current therapy. For high-risk patients, we determine the dosage regimen using a pharmacokinetic computer program based on the determined drug levels.

We perform examinations mainly for our patients at the Nitra University Hospital, as well as for ŠN Zobor, the Psychiatric Hospital in Veľké Zálužie, the Hospital in Topoľčany, and specialized clinics in Nitra, Topoľčany, Zlaté Moravce, Šahy, Šaľa, and Galanta. Since 1992, we have determined over 110,000 drug levels.

 

Current staff composition, qualifications, contacts

MUDr. Karin Máčalová – clinical pharmacologist, diabetologist, internist – ext. 867

Organizationally assigned under the Internal Clinic of FN Nitra

Qualifications:

  • attestation in internal medicine, clinical pharmacology, diabetology, metabolic disorders and nutrition

(more information on the page of the diabetology clinic and the Internal Clinic of FN Nitra)

MUDr. Marek Rác – clinical pharmacologist, hepatologist, internist – ext. 492

Qualifications:

Organizationally assigned under the Internal Clinic of FN Nitra

  • attestation in internal medicine, clinical pharmacology, hepatology

(more information on the page of the hepatology clinic and the Internal Clinic of FN Nitra)

PharmDr. Mária Göböová, PhD. – clinical pharmacist – ext. 370

Qualifications:

  • attestation in clinical pharmacy level I and II, attestation in pharmacy,
  • certificate in clinical trials of drugs and products from the Slovak Medical University in Bratislava,
  • rigorous examination in the field of pharmacy at the Faculty of Pharmacy of Comenius University in Bratislava,
  • doctoral studies in the field of pharmacology at the Faculty of Pharmacy of Comenius University in Bratislava

Other activities:

  • Chief Expert for Clinical Pharmacy of the Ministry of Health of the Slovak Republic
  • professional guarantor for the field of clinical pharmacy at SZU in Bratislava
  • scientific secretary of the Clinical Pharmacy Section, SFS, o.z. SLS
  • member of the state examination board and the departmental examination board for the accredited doctoral study program in clinical pharmacy at the Faculty of Pharmacy of Comenius University Bratislava.
  • chairwoman of the Ethics Committee, member of the Commission for Rational Pharmacotherapy and Drug Policy, member of the Commission for Anti-infective Treatment of FN Nitra

PhDr. Monika Fábriková – laboratory technician – ext. 243

organizationally assigned under the Department of Laboratory Medicine of FN Nitra

Possibilities for professional internships (based on the approval of the FN Nitra management)

Undergraduate education:

  • students of the Faculty of Pharmacy of Comenius University in Bratislava, students of other faculties (medical faculties, faculty of nursing, public health, and other faculties for the education of healthcare professionals), diploma theses, student scientific works

Postgraduate education:

  • in the field of clinical pharmacy within rigorous, doctoral studies, and attestation preparation

Professional internships:

  • therapeutic drug monitoring, clinical pharmacy

Spectrum of monitored drugs at the OKF FN Nitra and recommended collection times

Group Drug Collection time Steady state
(first collection from patient)
ANTIBIOTICS amikacin
gentamicin
0-30 min. before dose administration
30 min. after completion of i.v. administration
3rd – 4th dose
vancomycin 0-30 min. before dose administration
60 min. after completion of i.v. administration
CARDIOVASCULAR DRUGS digoxin
quinidine
before dose administration 5-7 days
2 days
ANTIASTHMATICS theophylline before dose administration 2 – 6 days
ANTIEPILEPTICS carbamazepine
phenobarbital
phenytoin
valproate
before dose administration 2 – 6 days
10 – 25 days adults: 8 – 20 children
4 – 24 days
2 – 4 days
TRICYCLIC ANTIDEPRESSANTS amitriptyline
imipramine
clomipramine
before dose administration 3 – 8 days
2 – 5 days
7 – 14 days
IMMUNOSUPPRESSANTS cyclosporine A tacrolimus before dose administration;
in case of organ transplantation 2 hours (+/- 10 min.) after cyclosporine dose administration
3 – 5 days
(collection into EDTA tube!!)
OPIATES morphine
codeine
heroin
before dose administration
heroin – toxicol. determination
after 14 – 24 hours of treatment
BENZODIAZEPINES all with BZD structure mainly toxicological determinations
AMPHETAMINE/METAMPH mainly toxicological determinations
CANNABINOIDS mainly toxicological determinations

Contacts

The area code before the extension is 037 / 6545 + extension

Head of Department – laboratory diagnostician OLM, OKB RNDr. Helena Pappová 409
Head laboratory technician OLM Mgr. Eva Vargová 847
Laboratory diagnostician OKIA RNDr. Monika Germániová 409
Laboratory diagnostician OKB Ing. Gabriela Kovárová 409
Laboratory diagnostician LLG RNDr. Andrea Kollárová,

RNDr. Alexandra Pôbišová, PhD., MPH

735
Biological material reception 417
Clinical Biochemistry Section:
Emergency medicine laboratory 413
Biochemical laboratory 490
Clinical Hematology Section:
Hematology laboratory 296
Hemostasiology laboratory 327
Clinical Immunology Section:
Laboratory 717
Clinical Genetics Section:
Genetics laboratory 243
Pharmacology laboratory 243
Blood Bank:
Sample reception 351

Our Team

Chief Physician