The Central Operating Theatre Department (COS) comprises 12 operating rooms and one autopsy room. In the Surgical Disciplines Pavilion, there are 6 operating rooms dedicated to vascular surgery, neurosurgery, surgery, traumatology, and orthopedics. In the Gynecology-Urology Pavilion, there are 6 operating rooms dedicated to urology, otorhinolaryngology and maxillofacial surgery, gynecology, and plastic surgery.
The Central Sterilization Unit carries out decontamination and sterilization of materials for the operating rooms, outpatient clinics, departments, and clinics of Fakultná nemocnica Nitra, as well as for private healthcare companies.
